Basic Information
VIS ID
TVIS44015533
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p12
Reference genome
GRCh37/hg19
Start
120453722/119911099 (Hg38)
End
120453722/119911099 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/2816371; hsa-mir-1182/Downstream/25939488;
Nearest TSS
ENST00000473358/Upstream/14604; ENST00000608123/Downstream/12806;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/14502, chr1-CpG: 95/Downstream/157635
Nearby gene
NOTCH2(-454) ;
Nearest cancer related gene
NOTCH2(TSG, -454) ;
Upstream sequence
TACTCTCCTTTTTTGGCTTTCACGTCTGGGAGTGCCCCGAGTCCTCCCTGCATAATCAAAGGCTAGCATTCAAGACTTAAAATTGCAGGGGCAGGATGTG
Downstream sequence
GTCAGCCACCCAATGGCCTGCAACCTGGATCCACTGAAGCAGGTTTTCATGGAGCAATTTAGTTCCCAAATAGTTTGCAAGTGGCAACTTGAGCTCTGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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