Basic Information
VIS ID
TVIS44015534
Fusion event
HTLV-1-LOC107984917 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.22
Reference genome
GRCh37/hg19
Start
12278632/12218575 (Hg38)
End
12278632/12218575 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
LOC107984917
Nearest miRNA
hsa-mir-12136/Upstream/26802; hsa-mir-101-1/Downstream/360382;
Nearest TSS
ENST00000473358/Upstream/26737; ENST00000476169/Downstream/11457;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/26647, chr1-CpG: 77/Downstream/11322
Nearby gene
TNFRSF1B(+9355) ;
Upstream sequence
taccatcctgggcaacatagggagacctcgtctctaccaaaaaATTAGCTAGATTGCTtgagctgtgatggtgccactgcactccagcctgggtgacaga
Downstream sequence
gcgagaccctgtccccaaaaaaCCCCAAAATACCACAGTTGAGAAAGTGAGGTTGCAtcatttcaactcggtaactgtcctgcgagataggcaaggtact
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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