Basic Information
VIS ID
TVIS44015535
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37/hg19
Start
133142/133142 (Hg38)
End
133142/133142 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
CICP27 ; LOC100996442
Nearest miRNA
hsa-mir-1302-2/Upstream/102639; hsa-mir-101-1/Downstream/54749;
Nearest TSS
ENST00000473358/Upstream/3925; ENST00000496488/Downstream/424;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/103405, chr1-CpG: 30/Downstream/1982
Nearby gene
LOC729737(-1631) ;
Upstream sequence
CAAGATGAGAAGATGCTCCAGCTGCAGTCCAAAGCCCAACACCCCCAAGTGTGCCATGTGTGATGGGGACAGCTTCCCCTTTGCCTGTACAGGTGGAGAA
Downstream sequence
GCCGAGGACAGGCTCAGGGAACCGGAGACCAAGAAGGCGCTGTCCTCTTCACTGCATGTACCCTGGACCAGTGCCGGCCCTGATCATGCAGCTCTTCCAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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