Basic Information
VIS ID
TVIS44015540
Fusion event
HTLV-1-PRPF3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
150322121/150349645 (Hg38)
End
150322121/150349645 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
PRPF3
Nearest miRNA
hsa-mir-101-1/Upstream/1961282; hsa-mir-1182/Downstream/142700;
Nearest TSS
ENST00000473358/Upstream/961; ENST00000369067/Downstream/13446;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/27954, chr1-CpG: 16/Downstream/14710
Upstream sequence
TTACCTTTGgatatagtgaaggaagtactagacttaagaatataaagttaggaggctgggcagtgctgcttattagctgtgcaatctgggcaagacactt
Downstream sequence
aatgtcaaattctgttgccttagctattgttctctatattgtcaagtttttgagaatgaaattagataattatgtgatagtgcttcataaaatgtgaCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate