Basic Information
VIS ID
TVIS44015583
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
188016891/188047760 (Hg38)
End
188016891/188047760 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1K
Nearest miRNA
hsa-mir-101-1/Upstream/7609370; hsa-mir-1182/Downstream/4668568;
Nearest TSS
ENST00000473358/Upstream/406144; ENST00000569873/Downstream/170640;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1366811, chr1-CpG: 56/Downstream/4760742
Upstream sequence
TTGCTTCTACCTCCAGAATTCTGTCTCTGTAAAAGAGAAAAAAATTCTTCAGGGCAAAGAAGGATTTCATATTTCCTTGATTATTAGCTTTACCTTTTCA
Downstream sequence
GTTGAAAGTGGTTAATAAGTCATTCAGCACACATGCATATTAAAAAGTCACTAATGTCTTGTCCTATAGACATTGAACACCATACCTACACTTAGCAGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate