Basic Information
VIS ID
TVIS44015585
Fusion event
HTLV-1-LOC105371657 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
189217983/189248852 (Hg38)
End
189217983/189248852 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
LOC105371657
Nearest miRNA
hsa-mir-101-1/Upstream/8810462; hsa-mir-1182/Downstream/3467476;
Nearest TSS
ENST00000473358/Upstream/343164; ENST00000419614/Downstream/526613;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/2567903, chr1-CpG: 56/Downstream/3559650
Nearby gene
BRINP3(No orient, 848814)
Upstream sequence
AAATAGTATCAGAAAATTTGATGTGTCATTGTATACAATCACTTTTGAAGCATGGGGGAGAGAGTTTAGAATATTTCATAAAAGAAGCAGCATCAGGTTT
Downstream sequence
ATGTGGACCTACAAACTGATTTAAATTGGAATTTTTACATCAAATATATGTTTTTTTTTATGCCATGCAtctgccactttctaacacatgactttgggca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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