Basic Information
VIS ID
TVIS44015587
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
191145298/191176168 (Hg38)
End
191145298/191176168 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1K
Nearest miRNA
hsa-mir-101-1/Upstream/10737778; hsa-mir-1182/Downstream/1540160;
Nearest TSS
ENST00000473358/Upstream/24658; ENST00000430776/Downstream/52299;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/4495219, chr1-CpG: 56/Downstream/1632334
Nearby gene
LINC01720(+374510) ;
Upstream sequence
atcaagtaatttaactttttcttacaatgtcatgacttttctctgctttttgggagcacttccagtatcactagtggcacttcccatgggttccatggtg
Downstream sequence
taattcaaggtttacagtattgcatgaaacatgataaaatatgtgaaaactatgagagatcactttttgctgcaatactcagtttactaaagagagaaac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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