Basic Information
VIS ID
TVIS44015598
Fusion event
HTLV-1-LOC105378590 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37/hg19
Start
1968893/2037454 (Hg38)
End
1968893/2037454 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
LOC105378590
Nearest miRNA
hsa-mir-12136/Upstream/697746; hsa-mir-101-1/Downstream/1090521;
Nearest TSS
ENST00000473358/Upstream/8535; ENST00000484419/Downstream/12197;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/7043, chr1-CpG: 22/Downstream/5793
Nearby gene
GABRD(+6701) ;
Upstream sequence
ATCAAGACTAGCTCTGCCTTGCTGGGACGTGAAATCCACCATCATAAATGGGTGCTTCCATGTCCCCCCTGATCTAGCATCCTCCACACCATCCCAGCCG
Downstream sequence
CGACCGCCCATTCTCACCAGAGCCCGTCAGCCAGGACCGTCGCCTGGCTGCTTGGACTGTGACGCGAGCCATCGCCTCCCTGCTTGGACCGTGCAGAGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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