Basic Information
VIS ID
TVIS44015599
Fusion event
HTLV-1-LRRN2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
204608100/204638972 (Hg38)
End
204608100/204638972 (Hg38)
Orient
+
Location type
Intronic
Target gene
LRRN2
miRNAs that regulate target gene
hsa-mir-671-5p
Nearest miRNA
hsa-mir-101-1/Upstream/2635736; hsa-mir-1182/Downstream/809330;
Nearest TSS
ENST00000473358/Upstream/12197; ENST00000435021/Downstream/24900;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/122269, chr1-CpG: 100/Downstream/46032
Upstream sequence
CTGGCTAGTGGGACGCCACCCCCAGGCTCCTGCTCCCAGGCTGGGGAAGGGTTTTGGGGGCTCCGTGAGCCTGCTGAATGACCCTGCCCTGAGATGGCCA
Downstream sequence
TCGCCTGGCAGGGCAGCCTCAGCTCCCACCTTTGAAAGTCTTTCCCCTGTGAGCAAGTGGTGGCACGGCCCCCTGGGTAGCTCTGGAGAGGGCGATAGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate