VISDB Viral Integration Site DataBase

VIS ID

TVIS44015617

Fusion event

HTLV-1-SKI integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

p36.33

Reference genome

Start

End

2183294/2251855 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-195-5p ; hsa-mir-155-5p ; hsa-mir-590-3p ; hsa-mir-340-5p ; hsa-mir-99a-5p ; hsa-mir-744-5p ; hsa-mir-92b-3p ; hsa-mir-484 ; hsa-mir-149-5p ; hsa-mir-221-3p ; hsa-mir-196a-5p ; hsa-mir-92a-3p ; hsa-let-7b-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-7515 ; hsa-mir-125a-3p ; hsa-mir-552-3p ; hsa-mir-6505-5p ; hsa-mir-127-3p ; hsa-mir-4462 ; hsa-mir-433-5p ; hsa-mir-651-3p ; hsa-mir-548l ; hsa-mir-548n ; hsa-mir-3148 ; hsa-mir-203b-3p ; hsa-mir-5095 ; hsa-mir-7151-3p ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-584-3p ; hsa-mir-548d-3p ; hsa-mir-653-3p ; hsa-mir-548h-3p ; hsa-mir-2110 ; hsa-mir-3138 ; hsa-mir-3154 ; hsa-mir-4311 ; hsa-mir-4271 ; hsa-mir-4277 ; hsa-mir-548z ; hsa-mir-548ac ; hsa-mir-4667-5p ; hsa-mir-4700-5p ; hsa-mir-4725-3p ; hsa-mir-4747-5p ; hsa-mir-5196-5p ; hsa-mir-548at-3p ; hsa-mir-548ay-3p ; hsa-mir-6770-5p ; hsa-mir-6780b-5p ; hsa-mir-8089 ; hsa-mir-9500 ; hsa-mir-548bb-3p ; hsa-mir-369-3p ; hsa-mir-374a-5p ; hsa-mir-452-5p ; hsa-mir-655-3p ; hsa-mir-711 ; hsa-mir-374c-5p ; hsa-mir-4676-3p ; hsa-mir-892c-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-503-5p ; hsa-mir-564 ; hsa-mir-627-3p ; hsa-mir-374b-3p ; hsa-mir-1909-3p ; hsa-mir-3151-5p ; hsa-mir-3180-3p ; hsa-mir-3196 ; hsa-mir-3180 ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-6722-3p ; hsa-mir-6796-3p ; hsa-mir-6816-5p ; hsa-mir-6838-5p ; hsa-mir-6853-5p ; hsa-mir-936 ; hsa-mir-4282 ; hsa-mir-4435 ; hsa-mir-6516-5p ; hsa-mir-1301-5p ; hsa-mir-5002-3p ; hsa-mir-6502-5p ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-450b-5p ; hsa-mir-3680-3p ; hsa-mir-194-3p ; hsa-mir-6793-5p ; hsa-mir-6134 ; hsa-mir-6833-5p ; hsa-mir-128-2-5p ; hsa-mir-128-1-5p ; hsa-mir-6851-5p ; hsa-mir-6781-5p ; hsa-mir-3689d ; hsa-mir-140-3p ; hsa-mir-4699-3p ; hsa-mir-4708-3p ; hsa-mir-4693-3p ; hsa-mir-5002-5p ; hsa-mir-6829-5p ; hsa-mir-25-5p ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-558 ; hsa-mir-1205 ; hsa-mir-4752 ; hsa-mir-4420 ; hsa-mir-181b-3p ; hsa-mir-181b-2-3p ; hsa-mir-4800-5p ; hsa-mir-943 ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-3187-3p ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-455-3p ; hsa-mir-7158-3p ; hsa-mir-6499-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-486-3p ; hsa-mir-646 ; hsa-mir-7111-3p ; hsa-mir-5701 ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4723-3p ; hsa-mir-6769b-3p ; hsa-mir-3183 ; hsa-mir-3973 ; hsa-mir-6507-3p ; hsa-mir-4480 ; hsa-mir-1908-5p ; hsa-mir-1227-5p ; hsa-mir-1245b-3p ; hsa-mir-185-3p ; hsa-mir-2467-3p ; hsa-mir-3119 ; hsa-mir-3147 ; hsa-mir-3186-3p ; hsa-mir-342-5p ; hsa-mir-34a-5p ; hsa-mir-34c-5p ; hsa-mir-3607-5p ; hsa-mir-3670 ; hsa-mir-3678-3p ; hsa-mir-3942-3p ; hsa-mir-4255 ; hsa-mir-4260 ; hsa-mir-4283 ; hsa-mir-4425 ; hsa-mir-4467 ; hsa-mir-4489 ; hsa-mir-449a ; hsa-mir-449b-5p ; hsa-mir-4537 ; hsa-mir-4664-5p ; hsa-mir-4671-5p ; hsa-mir-4767 ; hsa-mir-5100 ; hsa-mir-524-3p ; hsa-mir-525-3p ; hsa-mir-548ao-3p ; hsa-mir-663a ; hsa-mir-6760-3p ; hsa-mir-6787-5p ; hsa-mir-6814-3p ; hsa-mir-6820-5p ; hsa-mir-6847-5p ; hsa-mir-6872-5p ; hsa-mir-7112-5p ; hsa-mir-1587 ; hsa-mir-3620-5p ; hsa-mir-4265 ; hsa-mir-4296 ; hsa-mir-4322 ; hsa-mir-4417 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4656 ; hsa-mir-4675 ; hsa-mir-4741 ; hsa-mir-5001-5p ; hsa-mir-762

Nearest miRNA

hsa-mir-12136/Upstream/912147; hsa-mir-101-1/Downstream/876120;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/22121, chr1-CpG: 179/Downstream/28726

Nearest cancer related gene

SKI(OG, No orient, 0)

Upstream sequence

TTTTCTAGAAAAATGAACCGCAAAGTATTTCTTTCCTCGTGAATGTCGACCATTTTCTCGAGTCTGGTTGTTGTTGGCCAGTGACACAAACCTGCAGCTT

Downstream sequence

CTCCCCTTCTTGCTTCCCTCCCCGCCCCTTGGCTCCGGGCACAGCGTGGCTGAACCGGCTTATCTGGCCTCGTCTCTGGAGGCCTCCCCAGCTGTCATGT