VISDB Viral Integration Site DataBase

VIS ID

TVIS44015627

Fusion event

HTLV-1-PCNX2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

q42.2

Reference genome

Start

End

233309013/233173267 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-154-5p ; hsa-mir-382-5p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-3613-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-4324 ; hsa-mir-4277 ; hsa-mir-584-3p ; hsa-mir-6874-3p ; hsa-mir-148b-5p ; hsa-mir-383-5p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-1304-3p ; hsa-mir-5007-5p ; hsa-mir-3664-5p ; hsa-mir-4797-5p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-5589-5p ; hsa-mir-6506-5p ; hsa-mir-4731-5p ; hsa-mir-619-5p ; hsa-mir-6504-3p ; hsa-mir-1283 ; hsa-mir-4438 ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-1200 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4714-3p ; hsa-mir-4722-3p ; hsa-mir-498 ; hsa-mir-544b ; hsa-mir-660-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6869-5p

Nearest miRNA

hsa-mir-101-1/Upstream/2153343; hsa-mir-1537/Downstream/450885;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/186877, chr1-CpG: 38/Downstream/122136

Upstream sequence

ttttttttttttctctttttaaagacagagcttcactcttgttgcccaggctggaatgcagtggcgcgatctcgctgcaacctccacctcccgggttcaa

Downstream sequence

gtgattctcctgcctcagcctcccaagtagctgagactagaggcatgtgccaccacacctggctaattttgtatttttagtagagatggggtttcaccat