VISDB Viral Integration Site DataBase

VIS ID

TVIS44015633

Fusion event

HTLV-1-AKT3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

q44

Reference genome

Start

End

243991515/243828213 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-122-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-519d-3p ; hsa-mir-29c-3p ; hsa-mir-124-3p ; hsa-mir-146b-5p ; hsa-mir-2054 ; hsa-mir-297 ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-6134 ; hsa-mir-7854-3p ; hsa-mir-4725-5p ; hsa-mir-545-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-4781-3p ; hsa-mir-3976 ; hsa-mir-6856-5p ; hsa-mir-646 ; hsa-mir-6758-5p ; hsa-mir-595 ; hsa-mir-503-5p ; hsa-mir-497-5p ; hsa-mir-195-5p ; hsa-mir-6838-5p ; hsa-mir-424-5p ; hsa-mir-15b-5p ; hsa-mir-374a-3p ; hsa-mir-361-5p ; hsa-mir-569 ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-873-5p ; hsa-mir-7-5p ; hsa-mir-552-5p ; hsa-mir-5582-5p ; hsa-mir-708-3p ; hsa-mir-548an ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-29b-1-5p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-20b-5p

Nearest miRNA

hsa-mir-101-1/Upstream/481958; hsa-mir-3124/Downstream/3373754;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/338752, chr1-CpG: 166/Downstream/21197

Upstream sequence

GACTGTCTATATAGAAGTAAACAATGGGTGAGTTAAATACTAAATATTAGTAAAGTTGATGTCAAACTAGTAATATTCTACAGATTATTAaatagttatt

Downstream sequence

tactatttaatatgtcccatgcagtctgataagagctaatcacacattatgagcttggattcctatacccatataaagtaggcacttttatcatctccat