Basic Information
VIS ID
TVIS44015634
Fusion event
HTLV-1-RCAN3AS integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
24823232/24496742 (Hg38)
End
24823232/24496742 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA1A
Target gene
RCAN3AS
Nearest miRNA
hsa-mir-12136/Upstream/567595; hsa-mir-101-1/Downstream/422603;
Nearest TSS
ENST00000473358/Upstream/40576; ENST00000374393/Downstream/5609;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/80193, chr1-CpG: 108/Downstream/5633
Upstream sequence
gcctgtaatcctagcactttgggagcctgagatgggcagatcacaaggtcaggagttcgagaccagcctggccaacatggtgaaaccctgtctctactaa
Downstream sequence
aaatacaaaaattagccagacatggtggcacatgcctataatcctagctactcaagaggctgagacaggaaaattgcttgaacccaggaggcagaggttg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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