VISDB Viral Integration Site DataBase

VIS ID

TVIS44015640

Fusion event

HTLV-1-TMEM50A integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

p36.11

Reference genome

Start

End

25685546/25359055 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-484 ; hsa-mir-149-5p ; hsa-mir-92a-2-5p ; hsa-mir-135b-3p ; hsa-mir-3934-3p ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-4525 ; hsa-mir-5010-5p ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6795-5p ; hsa-mir-6887-5p ; hsa-mir-7109-5p ; hsa-mir-6796-5p ; hsa-mir-215-3p ; hsa-mir-1304-5p ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-1224-5p ; hsa-mir-3915 ; hsa-mir-5192 ; hsa-mir-6844 ; hsa-mir-4784 ; hsa-mir-924 ; hsa-mir-3150b-3p ; hsa-mir-5007-5p ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-6890-3p ; hsa-mir-629-3p ; hsa-mir-6759-5p ; hsa-mir-4322 ; hsa-mir-4296 ; hsa-mir-4265 ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-7977 ; hsa-mir-4540 ; hsa-mir-6723-5p ; hsa-mir-4769-5p ; hsa-mir-4654 ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-4648 ; hsa-mir-6716-5p ; hsa-mir-3140-3p ; hsa-mir-15b-3p ; hsa-mir-627-3p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-6838-3p ; hsa-mir-374c-3p

Nearest miRNA

hsa-mir-12136/Upstream/335469; hsa-mir-101-1/Downstream/547307;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/20148, chr1-CpG: 151/Downstream/71019

Upstream sequence

tgttgcccaggctggtctcaaactcctgggctcaagcgatctgcccgccttggcctcccaaagtgctgggattacaggcatgagccactgtgtctggcTC

Downstream sequence

ATAGCCCCCATTTCATTTGGTGCCTGGGACTGCGCACCAGCTGCCCCATAGAGCATGCAGGCAGGCATCCCCATAGAGCATGCAGGCAGGCAGCCCCATA