Basic Information
VIS ID
TVIS44015668
Fusion event
HTLV-1-AGBL4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p33
Reference genome
GRCh37/hg19
Start
49319484/48853812 (Hg38)
End
49319484/48853812 (Hg38)
Orient
+
Location type
Intronic
Target gene
AGBL4
Nearest miRNA
hsa-mir-12136/Upstream/4308260; hsa-mir-101-1/Downstream/2206025;
Nearest TSS
ENST00000473358/Upstream/76843; ENST00000456002/Downstream/171783;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/76674, chr1-CpG: 34/Downstream/45070
Upstream sequence
TTATCCTTCAGATTCCCATGAGGTCTGTCTACCTCATGGCTGGGCTAGGTTGACTATAATTGCACTGCTTCAGGTCACAGCACATTACACTGGCCTACAA
Downstream sequence
GAGATATTCCCTGATGCCCCATAAGTGTAGAGACAGACTTATGCTGCTGCAGACCTTCAGCCTGTGGATTTAGACCTCCATCCCTGAACCAATGAGAACC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate