Basic Information
VIS ID
TVIS44015670
Fusion event
HTLV-1-AGBL4-IT1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p33
Reference genome
GRCh37/hg19
Start
49907010/49441338 (Hg38)
End
49907010/49441338 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
AGBL4-IT1
Nearest miRNA
hsa-mir-12136/Upstream/4895786; hsa-mir-101-1/Downstream/1618499;
Nearest TSS
ENST00000473358/Upstream/183927; ENST00000494555/Downstream/410180;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/542097, chr1-CpG: 34/Downstream/582407
Upstream sequence
tctggagaacaggcatgggaatggatattaagggtgtgggataatggtggaaggaacatagagttggatcaggctgcatttattgatttaggcacactaa
Downstream sequence
gaagggactctgcatttaatgttgcagctccaggaattaaaaaaggctctaatagtttatttgcttgattagctgaaatagggattaaaagatggtccac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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