Basic Information
VIS ID
TVIS44015682
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.31
Reference genome
GRCh37/hg19
Start
5635973/5575913 (Hg38)
End
5635973/5575913 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/2015123; hsa-mir-101-1/Downstream/286759;
Nearest TSS
ENST00000473358/Upstream/82856; ENST00000493807/Downstream/92342;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/803420, chr1-CpG: 43/Downstream/136083
Nearby gene
MIR4417(+11770) ;
Upstream sequence
AAAAACGCCTGTGGGCTCAGGAGATCTTAGCCCCGAGAGAGGAGGAGTTTGGAAGTTTTCCACCACTTACCTGCAGTTGTGGGGCCTCTGCCAGGCATCT
Downstream sequence
CTTCCCCAGATTGGAAGAAGATGCACCATTCCCCTTCCAGGCTTAACTGTGTCATCAAACTTGTTGATAGAAAGCCGACTCCCACCCAGGCTGATTCAAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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