Basic Information
VIS ID
TVIS44015692
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37/hg19
Start
67727601/67261918 (Hg38)
End
67727601/67261918 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1L
Nearest miRNA
hsa-mir-101-1/Upstream/633401; hsa-mir-11399/Downstream/921600;
Nearest TSS
ENST00000473358/Upstream/30065; ENST00000441640/Downstream/45446;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/126886, chr1-CpG: 139/Downstream/167534
Nearby gene
IL23R(+1951) ;
Upstream sequence
CAGCATTGTTTGATCTTCTGCAAATGTTTCCACTGCAGCGAGTGCCTCCTTTTCGCCCCCTAGAGTGGGAAGGAAGCTGCTTTCTCATTCTGTGGTGTCT
Downstream sequence
TAACCCACATCACTATTCAGCACAAAGGAGACACTTCTGATTCTGTCTTTGCCATTAGCCCTTGTTGGTCCCAATGGACTAGAAATTGAGGCTATACCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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