Basic Information
VIS ID
TVIS44015704
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
88030225/87564542 (Hg38)
End
88030225/87564542 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1D
Nearest miRNA
hsa-mir-101-1/Upstream/1206855; hsa-mir-11399/Downstream/6282290;
Nearest TSS
ENST00000473358/Upstream/192887; ENST00000436111/Downstream/341172;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/228993, chr1-CpG: 63/Downstream/898058
Nearby gene
LINC01364(No orient, 192887)
Upstream sequence
TTGTTAACAATGGTAATACAGTAATGATCTTTAATGATGGACTGTTGTATGAAATAGACTGACTGGGAAGAAAAGCTAGATGAAAACAGCTGTCATTTTA
Downstream sequence
TATCGCCAAACCCTGTTCTCACATGGACAAAGAGAGATCATGAATTCATGTCCCATAATGTGATGGAGAGGTATTATATCACTGTATGTCCACTGCCATT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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