Basic Information
VIS ID
TVIS44015711
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
92930334/92464777 (Hg38)
End
92930334/92464777 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1D
Nearest miRNA
hsa-mir-101-1/Upstream/6107090; hsa-mir-11399/Downstream/1382055;
Nearest TSS
ENST00000473358/Upstream/131535; ENST00000646852/Downstream/19177;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/165408, chr1-CpG: 494/Downstream/15532
Nearby gene
GFI1(-9984) ;
Nearest cancer related gene
GFI1(OG, -9984) ;
Upstream sequence
GTACTCCAACATCTTAGGGGAGGAGCCCTAGGGGTCATGGCTTTTCACAGCATGAGAATCAGAAGGAGAGGAAATAAGGGGGAAATGTCATGGCCACATT
Downstream sequence
AGTGTTCGCACACACACACCCAGGAAGGGGTGCCGGCACTATGACCTAGGGTAAGGCTATACTCTGTAGGGGTGTGGCTGTCATCCTGATTCTTGGGAAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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