Basic Information
VIS ID
TVIS44015723
Fusion event
HTLV-1-MIR548AA1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
100158493/99692937 (Hg38)
End
100158493/99692937 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA1M
Target gene
MIR548AA1
Nearest miRNA
hsa-mir-101-1/Upstream/1646766; hsa-mir-11399/Downstream/588304;
Nearest TSS
ENST00000473358/Upstream/9671; ENST00000477753/Downstream/19571;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/428158, chr1-CpG: 63/Downstream/156927
Upstream sequence
AGCAATCGAGACCTGCTTGCTACAGAGCACATTCTCTCAGTTCATCCTAAATTCTAGGGAATATTCTTGGCCCTGCCACTAGAACTGATCATCCCTGTTA
Downstream sequence
AAGTTTCAAGGGAAATAATGCTCTTTAGCTTCATTGAAATTAAAATATTTCATATAAGTGGAGTGACAATTAAAATAATCATGGTCTTGTTACAGAATTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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