Basic Information
VIS ID
TVIS44015733
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
108339644/107723188 (Hg38)
End
108339644/107723188 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/5290822; hsa-mir-10b/Downstream/1418302;
Nearest TSS
ENST00000437798/Upstream/180439; ENST00000419650/Downstream/30924;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/178732, chr2-CpG: 429/Downstream/103635
Nearby gene
GACAT1(No orient, 30924)
Upstream sequence
ttaagctgaggtaccgagggcaaggccctcatgacgggaatagtagcactataagaagggacacaggagagcattttctcccacttaccatgtgaagaca
Downstream sequence
caaggaaatcatagccatttgcaagccaggaagacagcccttaccataaccacgtaatcagcctattctggcatcctgattctgaacttccagcttctca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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