Basic Information
VIS ID
TVIS44015742
Fusion event
HTLV-1-DPP10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
116053805/115296229 (Hg38)
End
116053805/115296229 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
DPP10
Nearest miRNA
hsa-mir-1285-2/Upstream/1574861; hsa-mir-10b/Downstream/12127308;
Nearest TSS
ENST00000437798/Upstream/61773; ENST00000488208/Downstream/144643;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/133040, chr2-CpG: 48/Downstream/2518307
Upstream sequence
CTCTGGAGGCAGGGAGGAAACTCCAGATCAGACCCAGGTTTCTGGCTTGGGAGGTGGTGGTGGTGGTGAAGGAAGTGCAGTTGGTTAAGATAAGGAGATG
Downstream sequence
AGGTGAATTGCCAAATTTTCACCCAGATGCTCGGCGGCCTCTAAAGGTCGGTGGTGTTACCAGGCGCAAATTAGTAATGCTGGCTTTGAACTTACCTTGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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