Basic Information
VIS ID
TVIS44015746
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
117343116/116585540 (Hg38)
End
117343116/116585540 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/2864172; hsa-mir-10b/Downstream/10837997;
Nearest TSS
ENST00000437798/Upstream/770877; ENST00000489933/Downstream/1218634;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1422351, chr2-CpG: 48/Downstream/1228996
Nearby gene
DPP10(+740790) ;
Upstream sequence
TTTTCCTTTAAGTTGTTCTCTATTCTGATTTTTCTTACCTGCCACTTAACCTTCCACACCCTGATTCCCAGATGCCAGTATCAAGATTGGGGTACCTCAC
Downstream sequence
TGGTCTGTGTGGCAAAAAACATTTTGACCTGTTGCAGGAAAGCTTTTATTTTATTATGTATGTAACTTTCATGCTTCCAGCCATAATTTGGGGCCTATAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate