Basic Information
VIS ID
TVIS44015759
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
12789832/12649706 (Hg38)
End
12789832/12649706 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3681/Upstream/450505; hsa-mir-10b/Downstream/87661;
Nearest TSS
ENST00000437798/Upstream/50719; ENST00000569860/Downstream/65709;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/864579, chr2-CpG: 204/Downstream/66793
Nearby gene
TRIB2(+67166) ;
Nearest cancer related gene
TRIB2(OG, +67166) ;
Upstream sequence
atcctggaaatgctttgcagcACAACCACCAGTTCTTTATTGAAGGTTGACCCTGGGGGTGCAGCTCAATGGCCACCACACTCCTCGGCACCATCCCCAC
Downstream sequence
CTCTGTGCAGCTTCTACACACCTGGAGTTACCTAATCCTCAGCCCTAGCTCGGGGCGGTTACTCTGTGTCCATCAGTCCATAGCTGGATCTCTCGGTGCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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