Basic Information
VIS ID
TVIS44015760
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
128844145/128086571 (Hg38)
End
128844145/128086571 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/662953; hsa-mir-10b/Downstream/3404589;
Nearest TSS
ENST00000437798/Upstream/58451; ENST00000430075/Downstream/4629;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/57898, chr2-CpG: 49/Downstream/4518
Nearby gene
UGGT1(+4609) ;
Upstream sequence
agtggggggtgcaaactatcaacatacataaaacagaaaaaaatagaaaaggtggaggagcGATAGTAATAGTTTGAGGACTGAACTTCAAAAAGTCAGG
Downstream sequence
AAAGGCCCtttgtttttgtttgtttttttgagacagagtctcgctctgtcacccaggatagagtgcagtggcgtgatctcagctcactgcaacctctgcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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