Basic Information
VIS ID
TVIS44015778
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
148453696/147696127 (Hg38)
End
148453696/147696127 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2S ; FRA2K
Nearest miRNA
hsa-mir-128-1/Upstream/7109442; hsa-mir-10b/Downstream/1634151;
Nearest TSS
ENST00000437798/Upstream/816218; ENST00000487959/Downstream/148390;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1108316, chr2-CpG: 79/Downstream/147584
Nearby gene
ACVR2A(+148390) ;
Upstream sequence
gaatcacatagctgtggatggtggaggtaagatttgtacctaggtctgtctgacttccaaactggtaccccgtttcTCTATTCTGGCTTGTGCCACAATC
Downstream sequence
CCAGTGACAAGAAAAGATCATTTACTACCAGCCCCTATTTTCCCAGGGTTCCTCGCACAGTTTGTGGATTATACAGCCTCTCGCTGCTTTCTTCCAAGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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