Basic Information
VIS ID
TVIS44015783
Fusion event
HTLV-1-NBAS integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
15405534/15265410 (Hg38)
End
15405534/15265410 (Hg38)
Orient
-
Location type
Intronic
Target gene
NBAS
miRNAs that regulate target gene
hsa-mir-432-5p
Nearest miRNA
hsa-mir-3125/Upstream/2527966; hsa-mir-10b/Downstream/4083019;
Nearest TSS
ENST00000437798/Upstream/26724; ENST00000438178/Downstream/152171;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/629725, chr2-CpG: 27/Downstream/295605
Upstream sequence
cttgttgaactttggccaatcactctctagtaatctgaccctcagaccagagatgataatacttgcttaataatcaccctcacaagatgtgtgtgaatat
Downstream sequence
caaatgagctagggtataggaaaATTATAATCCTCAAATTCAGAACTCACTATCATGCTATCTTGTATTCCTTGCTTTGTTTTTGTGAGTGAATACACTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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