Basic Information
VIS ID
TVIS44015786
Fusion event
HTLV-1-LOC105373693 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
155387989/154531477 (Hg38)
End
155387989/154531477 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC105373693
Nearest miRNA
hsa-mir-128-1/Upstream/3163066; hsa-mir-10b/Downstream/4655358;
Nearest TSS
ENST00000437798/Upstream/71620; ENST00000493505/Downstream/166340;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/658072, chr2-CpG: 141/Downstream/166016
Nearby gene
LOC100144595(No orient, 74039)
Upstream sequence
TCTGGGAAGACTGATGAAAAGAGTGATTTAAATTAGTTGATGAATTATTATGGCTAGAAACTTTCTTGAAAAATGAGGACTACTGAGGCAAGATGCAAAG
Downstream sequence
AATATGTTGAGTGTGGATTAGTGTTCGTAGATAGTCAGACCCCCTGGTAAAAGCAGGAAGTTAGAGGTTGATGATGAAATGCTGGAAATTAAGTTCCTAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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