Basic Information
VIS ID
TVIS44015794
Fusion event
HTLV-1-NOSTRIN integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
169678235/168821725 (Hg38)
End
169678235/168821725 (Hg38)
Orient
+
Location type
Intronic
Target gene
NOSTRIN
Nearest miRNA
hsa-mir-128-1/Upstream/238707; hsa-mir-10b/Downstream/6345908;
Nearest TSS
ENST00000437798/Upstream/10391; ENST00000486873/Downstream/21327;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/364613, chr2-CpG: 22/Downstream/68484
Upstream sequence
gtaaggggagagtggcgaggatccttttttagacggggcaaacctctgaggcagtgatgttcgagcagctcctgttggggatgacacaaaggagaatacc
Downstream sequence
acgtggttatgtagcagaagctctcggcagaggccacagcaagtgcaaaggccctgaggcaggatggcagttggccactgaataggagtagaatcagcca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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