Basic Information
VIS ID
TVIS44015799
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
177705145/176840417 (Hg38)
End
177705145/176840417 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
LOC105373757 ; LOC107985966
Nearest miRNA
hsa-mir-10b/Upstream/239365; hsa-mir-1244-1/Downstream/372309;
Nearest TSS
ENST00000437798/Upstream/21107; ENST00000432457/Downstream/8986;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/202052, chr2-CpG: 98/Downstream/372040
Nearby gene
LINC01117(No orient, 184459)
Upstream sequence
tcccatagaaaggtcagcgtggccctgtgtgatctggccactgactgcccactccatcacatcatccccctcttgcttgttctctaggcttctggcacac
Downstream sequence
tggccttctttctgttccttgaatgacaatgtttcttcctaccacaggacttttaaacatgatgttctcactgccatcatccttcagacagcccaaatgt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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