Basic Information
VIS ID
TVIS44015800
Fusion event
HTLV-1-LOC105373757 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
177712286/176847558 (Hg38)
End
177712286/176847558 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
LOC105373757
Nearest miRNA
hsa-mir-10b/Upstream/246506; hsa-mir-1244-1/Downstream/365168;
Nearest TSS
ENST00000437798/Upstream/28248; ENST00000432457/Downstream/1845;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/209193, chr2-CpG: 98/Downstream/364899
Nearby gene
LINC01117(No orient, 191600)
Upstream sequence
CTCCCTTATTTTAATGATCTATCACAATTAGATAACTTCTTATTTATAACACTATTTTTGCAGTCACGAAGAAATACAAGAAAAGTGATGACCAAAATGA
Downstream sequence
CTTTAGAAGTCAGCCTCGGACATTATTTTCTGCTATTAGTCCTTACCAATGTCAAGTGCAAAATTTAAATTAACAAGCACTTCCCTTATTGGAATGACTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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