Basic Information
VIS ID
TVIS44015809
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
190091816/189227090 (Hg38)
End
190091816/189227090 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/93979; hsa-mir-1244-1/Downstream/17556144;
Nearest TSS
ENST00000437798/Upstream/47211; ENST00000631047/Downstream/214343;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/934098, chr2-CpG: 26/Downstream/214341
Nearby gene
COL5A2(-47211) ;
Upstream sequence
GAAAAAAGGAAACTAGCAAATTCTTCTAAACAGAAATCTACACATGCAAAGCCCAGAAAAGACACATCCACAGAAAAACtttgagaggccttcagaatct
Downstream sequence
ctacttgggccaattggtgaaagtttttctctattataaagctagtttacaaagagtgagagaggtggtttgtattttcaaatatccagacaccaacaca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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