Basic Information
VIS ID
TVIS44015813
Fusion event
HTLV-1-HIBCH integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
191131825/190267099 (Hg38)
End
191131825/190267099 (Hg38)
Orient
+
Location type
Intronic
Target gene
HIBCH
Nearest miRNA
hsa-mir-10b/Upstream/1133988; hsa-mir-1244-1/Downstream/16516135;
Nearest TSS
ENST00000437798/Upstream/14803; ENST00000430311/Downstream/13969;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/85996, chr2-CpG: 45/Downstream/52498
Upstream sequence
aaatgcctcggcctcccaaaatgctgggattacaggcaggagccactgtacctggccAAGATTAGtcatttttatttttattatttttattttttatttt
Downstream sequence
aGAAGACCAATTCTGTCCACAGTGTATGAATGTTCTAGGTGAAGCTGGGGTGATGGGGAGAGTGAGGTGAAGACAACATCTACAAATCTCATGACttttt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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