Basic Information
VIS ID
TVIS44015816
Fusion event
HTLV-1-LOC105376755 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
196009537/195144813 (Hg38)
End
196009537/195144813 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105376755
Nearest miRNA
hsa-mir-10b/Upstream/6011702; hsa-mir-1244-1/Downstream/11638421;
Nearest TSS
ENST00000437798/Upstream/118443; ENST00000413290/Downstream/303719;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2948727, chr2-CpG: 150/Downstream/512018
Upstream sequence
CTGCTAGTATCTGTCACATGGCTGCATGCCGGACTAATCTCTGATGCTTTCCTCGAGTTCTTTGCTCTGAGTCTTCTCCAGCTTACCTTCCCAACACTTC
Downstream sequence
CCCATAGGCTTAGAACTGATGCTTGTCTCTCAGCCTAGGTAGCCACATGCAAGAACATGAAGAACCAGAGCCACCCAGTAGGAAGGCAAGATCAGCTATT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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