Basic Information
VIS ID
TVIS44015818
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
198575449/197710725 (Hg38)
End
198575449/197710725 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2I
Nearest miRNA
hsa-mir-10b/Upstream/8577614; hsa-mir-1244-1/Downstream/9072509;
Nearest TSS
ENST00000437798/Upstream/5356; ENST00000487695/Downstream/45720;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/4501, chr2-CpG: 166/Downstream/74302
Nearby gene
MARS2(+2335) ;
Upstream sequence
ACCAGTAGTTGGTCAGGTTGTGAGCCCTCAATGAGGATGACATCATCATGAAGTGAGACCTGGAGTGCTGGTGGGTCCTTGCCTTGTCTTTTGTCAGAAA
Downstream sequence
GTGAATATCAATGGACCTAAAAGGGTGTAGACAtattgacagattattgacagattattattattattatacatattattatatgtataataataatatg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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