VISDB Viral Integration Site DataBase

VIS ID

TVIS44015821

Fusion event

HTLV-1-ICA1L integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q33.2

Reference genome

Start

End

203697377/202832654 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-218-5p ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-378a-5p ; hsa-mir-197-3p ; hsa-mir-4662a-5p ; hsa-mir-193b-5p ; hsa-mir-1193 ; hsa-mir-1976 ; hsa-mir-136-5p ; hsa-mir-4716-5p ; hsa-mir-2392 ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-3149 ; hsa-mir-452-3p ; hsa-mir-589-3p ; hsa-mir-6878-3p ; hsa-mir-190a-3p ; hsa-mir-6744-3p ; hsa-mir-4312 ; hsa-mir-4757-5p ; hsa-mir-150-5p ; hsa-mir-212-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-1295b-3p ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-566 ; hsa-mir-6789-3p ; hsa-mir-2276-3p ; hsa-mir-6787-3p ; hsa-mir-1304-3p ; hsa-mir-4485-5p ; hsa-mir-6736-3p ; hsa-mir-6890-3p ; hsa-mir-5089-5p ; hsa-mir-4715-3p ; hsa-mir-4727-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6814-5p ; hsa-mir-5697 ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-562 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-1203 ; hsa-mir-6894-3p ; hsa-mir-4763-5p

Nearest miRNA

hsa-mir-10b/Upstream/13699543; hsa-mir-1244-1/Downstream/3950580;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/58220, chr2-CpG: 106/Downstream/38548

Upstream sequence

ctgaaaatattagaaaacaagtaaaactcaaactctccagttacaaagttcagtaactgtaatttaaaattcactgcagctggatgtggaggctcacacc

Downstream sequence

tgtaatcccagcattttgggaggctgatacaagaggatctcttgagccctgaagtttgaggttacagtgagctatgattatgccactgcactcctgcctg