Basic Information
VIS ID
TVIS44015823
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
20633075/20433314 (Hg38)
End
20633075/20433314 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3125/Upstream/1084809; hsa-mir-10b/Downstream/4895326;
Nearest TSS
ENST00000437798/Upstream/81080; ENST00000272233/Downstream/13760;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/82012, chr2-CpG: 157/Downstream/13353
Nearby gene
RHOB(+13757) ;
Nearest cancer related gene
RHOB(TSG, +13757) ;
Upstream sequence
TGTCAAGGCAGCCTCTCCCCCAAATCTTCCTCCTCTCTTTTCTGCATCTCTGTGCTGGGCTGGCTCCCTCCTCTCCCTCCACTTCTCTCTTGACTCCTTC
Downstream sequence
CTGGCCTTCTGGACCAGGTGCTTGCTTCTGGGACAAGCTCCAGGCCCTTTAAAAAAAATGTGCATCAATTTAGACTTTAGTCCCCTTTCAAGTCTCCTCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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