VISDB Viral Integration Site DataBase

VIS ID

TVIS44015825

Fusion event

HTLV-1-KLF7 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q33.3

Reference genome

Start

End

207946673/207081949 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-8085 ; hsa-mir-6878-5p ; hsa-mir-6731-5p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-6770-5p ; hsa-mir-4795-5p ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-28-5p ; hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-3163 ; hsa-mir-1277-5p ; hsa-mir-410-3p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-186-3p ; hsa-mir-521 ; hsa-mir-8485 ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-4328 ; hsa-mir-324-5p ; hsa-mir-4733-5p ; hsa-mir-4789-3p ; hsa-mir-2681-5p ; hsa-mir-3156-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-188-3p ; hsa-mir-4301 ; hsa-mir-3977 ; hsa-mir-501-5p ; hsa-mir-6826-5p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-3177-5p ; hsa-mir-4257 ; hsa-mir-4797-5p ; hsa-mir-511-3p ; hsa-mir-574-5p ; hsa-mir-6867-5p

Nearest miRNA

hsa-mir-10b/Upstream/298641; hsa-mir-1244-1/Downstream/28038;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/316513, chr2-CpG: 75/Downstream/84179

Upstream sequence

GTCAAAAAAAAAAAAAAAAAAGGATGAAGAAGGGTgctcacagttattgagtatgttacgatatgtaggcactatgctaagggttttcccaatatcacgc

Downstream sequence

catcctcaccaaccctccatggtaagtattCTCACGCTTTGTGTGTGTGTGTGTTGGGGGCAGAAAGGAGGGGGGTGAAGGAAACTGAGGCTAAGGTGTT