Basic Information
VIS ID
TVIS44015838
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q36.3
Reference genome
GRCh37/hg19
Start
228325377/227460661 (Hg38)
End
228325377/227460661 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/801868; hsa-mir-1244-1/Downstream/11471;
Nearest TSS
ENST00000437798/Upstream/72712; ENST00000486932/Downstream/11491;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/134876, chr2-CpG: 131/Downstream/11375
Nearby gene
MIR5703(No orient, 11471)
Upstream sequence
gcattctatGTACTTGGATAGTAATAGCATTCCAAATATTACTTATCCAATCCATAGTATTGGATATGTAAAAGCATAGAAAAAAGGTCTGGAAAGGTAA
Downstream sequence
CGATGTGCTGCGACTGCTGGACGAGGCGATGTGAATGGGAGAGTGTGAGCTGTGGGCTGGGGAACTTTTGGCTTTACTGGCtgtgttagcttcccagggc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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