Basic Information
VIS ID
TVIS44015870
Fusion event
HTLV-1-SRD5A2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.1
Reference genome
GRCh37/hg19
Start
31781983/31556913 (Hg38)
End
31781983/31556913 (Hg38)
Orient
-
Location type
Intronic
Target gene
SRD5A2
Nearest miRNA
hsa-mir-1301/Upstream/3560464; hsa-mir-10b/Downstream/975240;
Nearest TSS
ENST00000437798/Upstream/29971; ENST00000605811/Downstream/24154;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/322126, chr2-CpG: 99/Downstream/23310
Upstream sequence
TAATATTACACTATTGAGATCAATTTCAGTTCAGACATCCAGTAAGGGAAATGTCAGCAAAGGACGACAGacaactaatatttatatattgcgtactatg
Downstream sequence
ttccaggcaatgttctaagtactttgcccatattaactcatttaatctttataacaaccctaggagataggtattattattcccattctacagagaagga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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