Basic Information
VIS ID
TVIS44015895
Fusion event
HTLV-1-LOC105369165 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.2
Reference genome
GRCh37/hg19
Start
53411048/53183910 (Hg38)
End
53411048/53183910 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2D ; FRA2H
Target gene
LOC105369165
Nearest miRNA
hsa-mir-1301/Upstream/481295; hsa-mir-10b/Downstream/665212;
Nearest TSS
ENST00000437798/Upstream/273890; ENST00000295304/Downstream/422168;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/553924, chr2-CpG: 28/Downstream/583844
Nearby gene
MIR4431(-481295) ;
Upstream sequence
CCCTCTCTCTGCCATTGTGTCCACTTTTTTCAGCAAGATAGAAAACATTTAGAGGTTCCAGTTTAGGTCACACTCCCTTACTATTTTCCCACTGTCCCAC
Downstream sequence
AAGTTGTGTCAGCTTACCTTAACACCCTTTACCTCTCTACATTCTGAAACCTTTTATCTTTCTTTTGTGAATATCATCTTCAGTTCAGTATTACGATATT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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