VISDB Viral Integration Site DataBase

VIS ID

TVIS44015901

Fusion event

HTLV-1-PAPOLG integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

p16.1

Reference genome

Start

End

61006856/60779721 (Hg38)

Orient

-

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-33a-5p ; hsa-mir-16-5p ; hsa-mir-503-5p ; hsa-mir-548e-5p ; hsa-mir-7158-3p ; hsa-mir-203b-3p ; hsa-mir-31-5p ; hsa-mir-1827 ; hsa-mir-4680-5p ; hsa-mir-4649-3p ; hsa-mir-4538 ; hsa-mir-3123 ; hsa-mir-4453 ; hsa-mir-549a ; hsa-mir-586 ; hsa-mir-5700 ; hsa-mir-33b-5p ; hsa-mir-3658 ; hsa-mir-3653-3p ; hsa-mir-5680 ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-6883-3p ; hsa-mir-561-3p ; hsa-mir-7844-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-mir-4789-5p ; hsa-let-7f-2-3p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-653-5p ; hsa-mir-548s ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-653-3p ; hsa-mir-3926 ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-4711-5p ; hsa-mir-7112-3p ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-6849-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-1294 ; hsa-mir-4252 ; hsa-mir-455-3p ; hsa-mir-5008-3p ; hsa-mir-5694 ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6737-3p ; hsa-mir-7157-3p ; hsa-mir-7854-3p

Nearest miRNA

hsa-mir-1301/Upstream/392276; hsa-mir-10b/Downstream/1426105;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/22986, chr2-CpG: 97/Downstream/101269

Upstream sequence

ATATTGATTTTCTAGGACGTGGTATTTATTCCAACATGCTAGGATTCCTTGGTGGTGTCTCCTGGGCAATGCTAGTTGCAAGAACTTGCCAATTGTATCC

Downstream sequence

AAATGCAGCAGCATCTACTTTAGTTCATAAGTTCTTTTTAGTTTTTTCCAAGTGGTAAGTATTTACGTGTGTACTTTGACTGTTTACTAATCTCTACCTA