Basic Information
VIS ID
TVIS44015944
Fusion event
HTLV-1-LOC101928347 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
88469802/88170283 (Hg38)
End
88469802/88170283 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2L
Target gene
LOC101928347
Nearest miRNA
hsa-mir-1285-2/Upstream/87684; hsa-mir-10b/Downstream/642087;
Nearest TSS
ENST00000437798/Upstream/42167; ENST00000419759/Downstream/12;
Nearest CpG islands
chr2-CpG: 63/Target, None/Upstream, None/Downstream
Nearby gene
THNSL2(+12) ;
Upstream sequence
CACAGGGCTTCCCCCTCGTGATGCTTCCGGGATCGCGCACCGCTGCTCACGCACTCTCCTCTGTCCTGTGTCCTCCGTCCCCCGCCCCCCGCCCCATCCC
Downstream sequence
CAGGTCCTTCCCACTGCGAAGCTGAGAACCCTAGCTCCGGCCCCGACCGGAAGCCCCACCGCACCGTCAGGGACGCGGACTCGGGAGTGCGCACATTCGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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