Basic Information
VIS ID
TVIS44015965
Fusion event
HTLV-1-ATP2B2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
10440990/10399306 (Hg38)
End
10440990/10399306 (Hg38)
Orient
-
Location type
Intronic
Target gene
ATP2B2
Nearest miRNA
hsa-mir-12127/Upstream/4744; hsa-let-7g/Downstream/5096933;
Nearest TSS
ENST00000440867/Upstream/53237; ENST00000440266/Downstream/1719;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/40404, chr3-CpG: 19/Downstream/106188
Upstream sequence
CTTCATCCCGGAGGGCAGGACCAGGGCCACAGGGCTGTAACAATTTATTGAAATCTCATGTGGCCCTATGTTCTAAGAGGTCATTTGGGGCATTCCACGG
Downstream sequence
TCTCTCAGTGAGAccccgggggctttgcacttgctatctctctgcctggaatacttttttcttctcactgttctgattttaggtcaaatgcaaccttttc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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