VISDB Viral Integration Site DataBase

VIS ID

TVIS44015979

Fusion event

HTLV-1-ARHGAP31 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

q13.33

Reference genome

Start

End

119059392/119340545 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6770-3p ; hsa-mir-6825-5p ; hsa-mir-4730 ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-7106-5p ; hsa-mir-149-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-663a ; hsa-mir-6787-5p ; hsa-mir-1908-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-4706 ; hsa-mir-4749-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6873-5p ; hsa-mir-6760-5p ; hsa-mir-3680-3p ; hsa-mir-576-5p ; hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-4735-5p ; hsa-mir-133a-5p ; hsa-mir-138-5p ; hsa-mir-3189-5p ; hsa-mir-3692-5p ; hsa-mir-4758-3p ; hsa-mir-544a ; hsa-mir-548q ; hsa-mir-5699-5p ; hsa-mir-6071 ; hsa-mir-6131 ; hsa-mir-6738-3p ; hsa-mir-6828-3p ; hsa-mir-93-3p

Nearest miRNA

hsa-let-7g/Upstream/2490178; hsa-mir-12124/Downstream/744019;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/17137, chr3-CpG: 24/Downstream/61455

Upstream sequence

aCATCTAAGTCCAGCAGGATTTAGTGACCAATTAGATATAGGAGTAGCTCAAGTGTCTTTGAAAATTAGCACCCTTTGACCTTATGTGGGGCAGAGcctg

Downstream sequence

ggccacttgccagctgtgtgatgtgacaagacacgtatttctttgagattcagtttcctcctcttaaaaggagaatgacagttcttcccttacaaggtct