VISDB Viral Integration Site DataBase

VIS ID

TVIS44016004

Fusion event

HTLV-1-AMOTL2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

q22.2

Reference genome

Start

End

134074325/134355483 (Hg38)

Orient

-

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-27a-3p ; hsa-mir-6716-5p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-877-5p ; hsa-mir-4437 ; hsa-mir-6124 ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-6852-5p ; hsa-mir-6742-3p ; hsa-mir-939-3p ; hsa-mir-135a-3p ; hsa-mir-3158-3p ; hsa-mir-4446-3p ; hsa-mir-5088-5p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3714 ; hsa-mir-3125 ; hsa-mir-4662a-3p ; hsa-mir-548an ; hsa-mir-891a-3p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-2467-3p ; hsa-mir-6847-5p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-4779 ; hsa-mir-3123 ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-6862-3p ; hsa-mir-6784-3p ; hsa-mir-5088-3p ; hsa-mir-3620-3p ; hsa-mir-6865-3p ; hsa-mir-4668-3p ; hsa-mir-8063 ; hsa-mir-580-3p ; hsa-mir-4775 ; hsa-mir-3119 ; hsa-mir-3160-5p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-4251 ; hsa-mir-135b-5p ; hsa-mir-135a-5p ; hsa-mir-590-3p ; hsa-mir-6772-3p ; hsa-mir-4713-5p ; hsa-mir-7111-3p ; hsa-mir-1251-3p ; hsa-mir-4448 ; hsa-mir-4268 ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-186-3p ; hsa-mir-1343-5p ; hsa-mir-3660 ; hsa-mir-4476 ; hsa-mir-4526 ; hsa-mir-4645-3p ; hsa-mir-6077 ; hsa-mir-6856-3p ; hsa-mir-6876-5p ; hsa-mir-8065 ; hsa-mir-888-3p ; hsa-mir-939-5p

Nearest miRNA

hsa-let-7g/Upstream/2369552; hsa-mir-1224/Downstream/12321;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/41734, chr3-CpG: 20/Downstream/6065

Upstream sequence

TGCTTTCCTGAGCATCAGGAAAGAGTGGTGATGTCACAGCAAAGGAGGGAGGCGGTGGCTAAGAACATGCACATTCTTGAATGTCCTCTGCATGGTGCCT

Downstream sequence

GGCCTTCTGGATGGTTTCGGACAAAACTTTATGTGCTAGGTGGGAGTGGGAAAAGGAGTGGGGGAAGGATAAAGCCATCTTTGGACACCCACTCCCACTG