Basic Information
VIS ID
TVIS44016018
Fusion event
HTLV-1-SLC9A9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q24
Reference genome
GRCh37/hg19
Start
143236008/143517166 (Hg38)
End
143236008/143517166 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC9A9
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-let-7g/Upstream/9079260; hsa-mir-1224/Downstream/8048710;
Nearest TSS
ENST00000440867/Upstream/135828; ENST00000491798/Downstream/180983;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/395170, chr3-CpG: 217/Downstream/453725
Upstream sequence
tctttaacttttttttttTTCCTTCAGCAAGGGCTTTATTTATCAGAAGGGCATTACGCTTGACCTCCAAATTTGGCTGACAATTTACTGATGAGATTCA
Downstream sequence
TAACCTTTGAGTTGCTCTGGTATTTTGACATACTTGCTGGGTTCTGAGCCACATCCTGGAAGGCCACCATAACTTCTGGATCCTGCATGGCGGCAAGAAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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