Basic Information
VIS ID
TVIS44016021
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
150575913/150858126 (Hg38)
End
150575913/150858126 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA3D
Nearest miRNA
hsa-let-7g/Upstream/16420220; hsa-mir-1224/Downstream/707750;
Nearest TSS
ENST00000440867/Upstream/5642; ENST00000469268/Downstream/32510;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/78481, chr3-CpG: 223/Downstream/227083
Nearby gene
CLRN1(-68037) ;
Upstream sequence
actggaaggcccactgccccagggaatgaaggtcctctgagtcagaagccactaaccagatgatccagcagcaggactgagggtgcccggggcaagcgcc
Downstream sequence
agcccatgccatcgccctcacggagccccgggtatgcttgaccattgagggccacgaggttaactgtctcctggacactggtgcggccttctcagtttta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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