VISDB Viral Integration Site DataBase

VIS ID

TVIS44016049

Fusion event

HTLV-1-MCF2L2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

q27.1

Reference genome

Start

End

183022248/183304460 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-510-3p ; hsa-mir-6818-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-4738-3p ; hsa-mir-3923 ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-1273e ; hsa-mir-25-5p ; hsa-mir-7160-5p ; hsa-mir-658 ; hsa-mir-202-3p ; hsa-mir-4500 ; hsa-mir-98-5p ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-6087 ; hsa-mir-219b-3p ; hsa-mir-7162-3p ; hsa-mir-1247-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6888-5p ; hsa-mir-302f ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6883-5p ; hsa-mir-6799-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-383-3p ; hsa-mir-890 ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-7703 ; hsa-mir-500a-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-542-3p ; hsa-mir-661 ; hsa-mir-767-5p ; hsa-mir-6776-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-6742-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-508-5p

Nearest miRNA

hsa-let-7g/Upstream/6789309; hsa-mir-1224/Downstream/582340;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/49613, chr3-CpG: 126/Downstream/123179

Upstream sequence

GAGGCAAAAATACCCAGAACACTTGTTCTAAACAGCAAAGGCCCAGGTGCACTGGTTACCACCCCTACAAGATGACTGGAATACTCATTCCCTGGGCAGT

Downstream sequence

GAttttttttttttttttttttttgagatggaatcttgctctgtagctaggctggagtgcagtggcttgatctaggctcactgaaaattctgcctccggg